Harmony said an employee was fatally injured on March 15 at its Moab Khotsong mine in the North West Province, following an engineering-related incident.
The miner had declared a safety day and brought all its operations to a standstill on January 29, following two fatalities within 15 days that month.
"Safety is a foundational value at Harmony and it is of utmost importance that we ensure a safe working environment at all our operations," CEO Peter Steenkamp said yesterday.
There was no mention of an investigation into the latest fatality.
Harmony said its management team extended condolences to the deceased's family, friends and co-workers.
The high-grade Moab Khotsong mine, acquired from AngloGold Ashanti in 2018, was Harmony's most profitable operation for the six months ending December 31.
It had produced 211,938 ounces in FY20 - less than a year earlier due to seismic activity and COVID-19.
