Muttenz-headquartered Clariant expects to see growth across its core care chemicals, catalysis, natural resources, and plastics and coatings businesses.
The Trump US government is lowering company taxes and has generally overseen a period of increased business confidence, investment and employment over the past 12 months.
"Clariant is … excited about its plans for growth over the next four years," said Clariant North America head Deepak Parikh.
"In addition to investing further in R&D and manufacturing, we will invest in critical talent acquisition and development to upskill our organisation."
Clariant's global Oil & Mining Services business is headquartered in Houston, Texas, with Clariant Mining Services a supplier of chemicals and integrated services to the mining and fertiliser industries.
The group has more than 50 sites, 2,400 employees and annual turnover of about $1.25 billion in the US and Canada. Total group sales last year were US$6.6 billion.
North America would be Clariant's second biggest market at its $2bn billion targeted sales level.