The company said Wednesday the milestone marked the end of a 5% NSR royalty that the operation has been paying since the start of production in 2005.
At the current gold price, that translated to savings of about US$65/oz, which had already been incorporated into guidance, Alamos said.
Alamos also said the past week marked the successful completion of a voluntary relocation of residents of the town of Mulatos to Matarachi, which started in 2016.
"The Mulatos district still holds great potential and we look forward to many more years of profitable production," CEO John McCluskey said.